Access SharePoint 2013 list item from a cross-domain scenario using C# CSOM

Hi,

We have created a provider-hosted app in SharePoint 2013.

The host web and the app web are in DIFFERENT DOMAINS.

Our Requirement :

It is possible to Access SharePoint 2013 list item from remote apps using the cross-domain library.

But I would like to use C#CSOM , to access the SharePoint 2013 list items. Is it possible to get data from SharePoint using server side code (C# CSOM).

Thanks